Scientific Advisory Committee on Alternative Toxicological Methods Meeting Final Documents
September 17 - 18 , 2024
Federal Register Notices September 17 - 18 , 2024
Scientific Advisory Committee on Alternative Toxicological Methods Meeting Meeting Materials
September 17 - 18 , 2024
Presentation Abstracts and Background Materials
- Session 1: ICCVAM Biennial Report
- Session 2: Validation Updates, NAMs Pipeline, and Future Directions
- Session 3: Developmental Neurotoxicology
- Session 4: Computational Resources
Public Comments
| Agenda Topic | Name, Affiliation, Sponsorship | Technical and Scientific Public Comments |
|---|---|---|
| Session 2: Validation Updates/NAMs Pipeline and Future Directions | Shagun Krishna, Catharine Krebs, and Elizabeth Baker, Physicians Committee for Responsible Medicine | Public comment received September 11, 2024 |
| Session 2: Validation Updates/NAMs Pipeline and Future Directions | Amy Clippinger and Katherine Groff, People for the Ethical Treatment of Animals (PETA) | Public comment received September 11, 2024 |
| Session 1: ICCVAM Biennial Report | Vicki Katrinak, Humane Society of the United States (HSUS) | Public comment received September 11, 2024 |
Scientific Advisory Committee on Alternative Toxicological Methods Meeting Presentations
September 17 - 18 , 2024
September 17, 2024
ICCVAM Biennial Report
- ICCVAM 2022-2023 Biennial Report
Nicole Kleinstreuer, PhD, NIEHS/NICEATM
Validation Updates
- Updates to OECD Guidance Document 34 on Validation of New and Updated Test Methods
Charles Kovatch, U.S. Environmental Protection Agency - Reviewing the Method Developers Forum - Follow-on Activities from the VWG Report
Emily Reinke, PhD, Inotiv (contractor supporting NICEATM) - In Vitro Inhalation Toxicity: A Case Study in Building Confidence in New Methods
Amy Clippinger, PhD, PETA Science Consortium International
NAMs Pipeline - Future Directions
- Advisory Committee to the Director, NIH, Recommendations on Catalyzing the Development and Use of New Approach Methods (NAMs) to Advance Biomedical Research
Ellen Gadbois, PhD, National Institutes of Health - Complement-ARIE: Complement Animal Research in Experimentation
Margaret Ochocinska, PhD, National Institutes of Health - Novel Alternative Methods (NAMs) Validation and Qualification Network (VQN)
Stacey Adam, PhD, Foundation for the National Institutes of Health
September 18, 2024
Developmental Neurotoxicity
- International Efforts Implementing NAMs for Assessing Developmental Neurotoxicity in Chemical Risk Assessment
Iris Mangas, PhD, European Food Safety Authority - Integrated Approaches to Testing and Assessment (IATA) Case Study for DNT
Helena Hogberg, PhD, NIEHS/NICEATM - The DNT In Vitro Battery: Establishing Confidence in and Using Data from the Battery
Timothy Shafer, PhD, U.S. Environmental Protection Agency - Integrating Screening Level Developmental Neurotoxicity (DNT) Information of Chemicals in a New Approach Methods (NAMs) Battery to Identify Compounds for Future Study
Christopher McPherson, PhD, NIEHS - Transfer of and Data Generation from the Developmental Neurotoxicity In Vitro Battery
Megan Culbreth, PhD, U.S. Food and Drug Administration
Computational Resources
- NICEATM's Integrated Chemical Environment (ICE): Updates, Enhancements, and Advances
Brad Reisfeld, PhD, Inotiv (contractor supporting NICEATM) - Collaborative Modeling Project for Acute Inhalation Toxicity (CoMPAIT)
Kamel Mansouri, PhD, NIEHS/NICEATM - Collection of Alternative Methods for Regulatory Application (CAMERA): New Interactive Database of Validated NAMs
Nicole Kleinstreuer, PhD, NIEHS/NICEATM