Scientific Advisory Committee on Alternative Toxicological Methods Meeting Final Documents
September 21 - 22 , 2023
Federal Register Notices September 21 - 22 , 2023
Scientific Advisory Committee on Alternative Toxicological Methods Meeting Meeting Materials
September 21 - 22 , 2023
Presentation Abstracts and Background Materials
- Session 1: Five Years into ICCVAM Strategic Roadmap
- Session 2: The Role of New Approach Methodologies (NAMs) in Improving Environmental Health Protection
- Session 3: NICEATM Computational Resources
Public Comments
| Agenda Topic | Name, Affiliation, Sponsorship | Technical and Scientific Public Comments |
|---|---|---|
| Session 1: Five Years Into the ICCVAM Strategic Roadmap | Patricia Bishop, Humane Society of the United States/Danielle Palermo, Human Society Legislative Fund | Public comment received September 14, 2023 |
| Session 1: Five Years Into the ICCVAM Strategic Roadmap | Amy Clippinger and Katherine Groff, People for the Ethical Treatment of Animals | Public comment received September 14, 2023 |
| Session 2: The Role of NAMs in Improving Environmental Health Protection | Amy Clippinger and Katherine Groff, People for the Ethical Treatment of Animals | Public comment received September 14, 2023 |
Scientific Advisory Committee on Alternative Toxicological Methods Meeting Presentations
September 21 - 22 , 2023
September 21, 2023
Five Years Into the ICCVAM Strategic Roadmap: Full Replacement of the Acute Tox Six-Pack
- Roadmap Implementation Plans: Update on Each of the Six-Pack Endpoints, How Close Are We to Replacement?
David Allen, PhD, Inotiv (contractor supporting NICEATM) - Modernizing the Acute Toxicity Six-Pack for U.S. EPA's Office of Chemical Safety and Pollution Prevention
Monique Perron, PhD, U.S. Environmental Protection Agency (EPA) - Beyond the Six-Pack: Strategic Roadmap Future Priorities?
Nicole Kleinstreuer, PhD, NIEHS/NICEATM
Five Years Into the ICCVAM Strategic Roadmap: Evolution of Validation
- ICCVAM Validation Work Group Report
John Gordon, PhD, U.S. Consumer Product Safety Commission - International Harmonization and Global Considerations: Organizational and Financial Aspects of Validation Studies
Anne Gourmelon, Organisation for Economic Co-operation and Development - International Harmonization and Global Considerations: Update of Guidance Document 34 and ICATM Position
Valerie Zuang, PhD, European Commission Joint Research Centre
September 22, 2023
The Role of NAMs in Improving Environmental Health Protection: Population Variability and Susceptibility
- Using NAMs to Address Variability and Susceptibility Across Populations: Report from the October 2022 Symposium Workshop
Helena Hogberg-Durdock, PhD, NIEHS/NICEATM - Building Confidence in New Evidence Streams for Human Health Risk Assessment
Weihsueh Chiu, PhD, Texas A&M University - Fruit Flies for Precision Toxicology
Brian Oliver, PhD, National Institute of Diabetes and Digestive and Kidney Diseases
The Role of NAMs in Improving Environmental Health Protection: Coordinated Responses to Contaminants of Emerging Concern
- An Interagency Initiative to Address Contaminants of Emerging Concern
David Balshaw, PhD, NIEHS - ICCVAM PFAS Workgroup
Natalia Vinas, PhD, U.S. Department of Defense
Computational Resources
- The Integrated Chemical Environment (ICE): Open-Access Tools to Support Chemical Evaluations
Victoria Hull, Inotiv (contractor supporting NICEATM) - OPERA: Open-Source QSAR Models for Regulatory Support
Kamel Mansouri, PhD, NIEHS/NICEATM - Web Application to Predict Skin Sensitization Using Defined Approaches
Kim To, PhD, Inotiv (contractor supporting NICEATM) - ChemMaps.com v2.0: Exploring the Environmental Chemical Universe
Alex Borrel, PhD, Inotiv (contractor supporting NICEATM)