Alimentary System

Tooth - Periodontal Pocket

    Narrative
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study. The opening of the pocket (arrow) to the oral cavity is not apparent because of the plane of section.
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study. The opening of the pocket (arrow) to the oral cavity is not apparent because of the plane of section.
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study (higher magnification of Figure 1). The periodontal pocket is lined by squamous epithelium (arrowhead and contains hair shafts (arrow).
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study (higher magnification of Figure 1). The periodontal pocket is lined by squamous epithelium (arrowhead and contains hair shafts (arrow).
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study. The opening of the pocket (arrow) to the oral cavity is adjacent to the tooth.
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study. The opening of the pocket (arrow) to the oral cavity is adjacent to the tooth.
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study (higher magnification of Figure 3). The pocket is lined by keratinizing squamous epithelium (arrow) and is surrounded by fibrosis and chronic inflammation.
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study (higher magnification of Figure 3). The pocket is lined by keratinizing squamous epithelium (arrow) and is surrounded by fibrosis and chronic inflammation.
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study (higher magnification of Figure 3). Hair shafts (arrow) are embedded in the periodontal tissue at the opening of the pocket.
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study (higher magnification of Figure 3). Hair shafts (arrow) are embedded in the periodontal tissue at the opening of the pocket.
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study (higher magnification of Figure 3). Hair shafts (arrows) are embedded in the periodontal tissue.
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study (higher magnification of Figure 3). Hair shafts (arrows) are embedded in the periodontal tissue.
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study. The opening of the pocket (arrow) to the oral cavity is not apparent because of the plane of section.
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study. The opening of the pocket (arrow) to the oral cavity is not apparent because of the plane of section.
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study (higher magnification of Figure 7). The periodontal pocket is lined by hyperplastic, keratinizing squamous epithelium and contains feed material.
    Tooth - Periodontal pocket in a male F344/N rat from a chronic study (higher magnification of Figure 7). The periodontal pocket is lined by hyperplastic, keratinizing squamous epithelium and contains feed material.

    Authors:

    Linda H. Kooistra, DVM, PhD, DACVP
    Pathologist
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Joel R. Leininger, DVM, PhD
    Senior Pathologist
    MedImmune
    Washington, DC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC